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زیست شناسی::
صفحات بالی
, that the disc is to be a leg disc and not a wing disc) occurs in the embryo and is mediated primarily by the Hox genes such as Ultrabithorax and Antennapedia.
DORSAL-VENTRAL AND PROXIMAL-DISTAL AXES The dorsal-ventral axis of the wing is formed at the second instar stage by the expression of the apterous gene in the prospective dorsal cells of the wing disc (Blair 1993; Diaz-Benjumea and Cohen 1993).
The vestigial gene remains active in the ventral portion of the wing disc (FIGURE 21.16A).
Thus, a battery of paracrine factors patterns the wing disc, giving each cell an identity along the dorsal-ventral, proximal-distal, and anterior-posterior axes.
(B) Wingless protein (purple) synthesized at the marginal juncture organizes the wing disc along the dorsal-ventral axis.
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